Stats on Vaccines and Vaxed

From this twitter post asking the question: "how much spike protein is being made by the body of a COVID vaccine injected person" re. the May 15, 2021.  mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

1/ start by estimating how much spike protein is being created by the mRNA vaccines

2/We know there is 30 microgram for Pfizer
3/Molecular weight is estimated at > 1.25 x10^6 gm/mole. (~330 gm per mole of nucleotide)

This comes out to
30 x 10^-6 grams/
1.25 x 10^6 gm/mole

=24 x 10^-12 moles

6 x 10^23 molecules/mole x 24 x 10^-12 moles =14.4x 10^12 molecules mRNA (14.4trillion)
4/14.4 trillion spike protein if 1 mRNA produces 1 spike protein

A more reasonable number is 1000 spike per mRNA

X1000 14,400 trillion spikes
 
5/So basically 30 micrograms of mRNA will theoretically produce about 14,400 trillion individual spike proteins (if 100% efficient)

6/Now we ask this. How many cells are transfected by the vaccines. In other words, how many mRNA molecules are in each LNP
7/Since we can estimate how many mRNA molecules there are (14.4 trillion for Pfizer), we must estimate how many LNP’s
8/First we must estimate the size of LNP

“Together with the mRNA, these components form particles of about 60–100 nm in size by using a rapid mixing production technique (Evers et al., 2018).”

9/So lets call it 80 nm and assume a spherical shape.
10/So LNP particles of 80 nm have a total weight of about 0.5 mg. Lipids are typically less dense than water but using the density of water we may estimate the volume of 0.5 mg as 5 x 10^17 cubic nm

SURVEY by Kaiser Family Foundation KFF COVID-19 Vaccine Monitor - April 2021 Liz Hamel , Lunna Lopes , Grace Sparks , Mellisha Stokes , and Mollyann Brodie May 06, 2021

US Adults Reporting to be COVID Vaxed
Fig. 1. US Adults Reporting to be COVID Vaxed

 

 

 

 

 

 

 

 

 

Parents Intentions for their Children to be Vaxed
Fig.2. Parents Intentions for their Children to be Vaxed

 

 

 

 

 

 

 

 

 

Parents Vaxed Status versus Intention to get Children Vaxed
Fig. 3. Parents Vaxed Status versus Intention to get Children Vaxed

 

 

 

 

 

 

 

 

 

 

Fig. 3 is surprising because 52% of the already vaxed parents plan to immediately vax or have already vaxed their children;  8% of those who haven't yet vaxed themselves (because they are waiting to see) yet, plan to immediately vax their children and 2% of parents who will not get the vaccine unless required or would never get it themselves say they will immediately vax their children.

Other Vaccination Information Sources:

https://ourworldindata.org/covid-vaccinations

https://ourworldindata.org/us-states-vaccinations

Are COVID vaccines helping or hurting?

Chile versus Venezuela Vaccine Rollout versus COVID Death rates
Chile versus Venezuela Vaccine Rollout versus COVID Death rates

 

 

 

 

 

 

 

 

 

 

 

 

 

Ireland's Vaccine Rollout vs. COVID Deaths
Ireland's Vaccine Rollout vs. COVID Deaths

 

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